{"title":"The Precision Collection","description":"\u003cp\u003eThe precision-dosed clinical collection. Bioretinol, marine ferment, peptide, and vitamin C serums paired with barrier-supporting day and night creams, an actives-forward routine built to visibly firm, smooth, and renew skin.\u003c\/p\u003e","products":[{"product_id":"anti-age-day-cream","title":"CELLULAR ANTI-AGING PROTECTIVE DAY CREAM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eThe Opuliss Skin Cellular Anti-Aging Protective Day Cream is a 50 ml \/ 1.69 fl oz daytime moisturiser built on a five-active stack anchored by Alteromonas Ferment Extract, a deep-sea marine biotech ferment, alongside a polyphenol berry stack of Lingonberry, Black Currant, and Elder Flower, and Multi-Weight Hyaluronic Acid (Hydrolyzed Hyaluronic Acid plus Sodium Hyaluronate). The formula is 100% natural origin, 21% organic origin, and vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Anti-Aging, Dry Skin, and Sensitive Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAlteromonas Ferment Extract, a deep-sea marine biotech ferment, supports the look of mature skin as an extracellular-matrix supporting active.\u003c\/li\u003e\n\u003cli\u003eLingonberry, Black Currant, and Elder Flower, a polyphenol berry stack, contribute antioxidant support against the visible signs of daytime environmental stress.\u003c\/li\u003e\n\u003cli\u003eMulti-Weight Hyaluronic Acid pairs surface-hydrating and stratum-corneum-penetrating molecular weights to help hydrate at multiple skin layers and soften the appearance of fine lines.\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Alteromonas Ferment Extract, a deep-sea marine biotech ferment, is used in cosmetic formulations for extracellular-matrix supporting cast and skin-tolerance positioning. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eAloe Barbadensis (Aloe) Leaf Juice, Simmondsia Chinensis (Jojoba) Seed Oil, Butyrospermum Parkii (Shea) Butter, Vaccinium Vitis-Idaea (Lingonberry) Fruit Extract, Echinacea Purpurea (Coneflower) Flower\/Leaf\/Stem Extract, Ribes Nigrum (Black Currant) Fruit Extract, Sambucus Nigra (Elder) Flower Extract, Persea Gratissima (Avocado) Oil, Tocopherol, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Alteromonas Ferment Extract.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Alteromonas Ferment Extract, a deep-sea marine biotech ferment. The Lingonberry, Black Currant, and Elder Flower polyphenol antioxidant stack; Multi-Weight Hyaluronic Acid, a humectant.\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eApply each morning to clean skin after toner and serum. Press gently into the face and neck. In the morning, layer over a broad-spectrum SPF 30 or higher for daily UV protection. Compatible with all Opuliss Skin actives.\u003c\/p\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e100% natural origin, 21% organic origin, vegan eligible. Contains naturally occurring fragrance allergens (Benzyl Salicylate, Limonene, Citral, Linalool). Contains Echinacea Purpurea (Coneflower) Extract, an Asteraceae botanical. If you have a known Compositae or ragweed allergy, patch test before regular use. The mineral pigments (Titanium Dioxide, Mica, Tin Oxide) provide an even-tone visual finish only and do not function as sunscreen, so layer with a dedicated SPF. Patch test on the inner forearm for 24 hours before facial use.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eThe polyphenol berry stack (Lingonberry, Black Currant, Elder Flower) contributes broad-spectrum antioxidant support against free-radical exposure. Echinacea Purpurea adds alkamide and polysaccharide compounds documented in cosmetic literature for skin-tolerance support. Alteromonas Ferment Extract is a deep-sea marine biotech ferment used in cosmetic formulations for extracellular-matrix support and skin-tolerance positioning.\u003csup\u003e2\u003c\/sup\u003e Multi-Weight Hyaluronic Acid pairs surface-hydrating and stratum-corneum-penetrating molecular weights, helping hydrate and soften the appearance of fine lines.\u003csup\u003e1\u003c\/sup\u003e The Shea Butter and Jojoba Seed Oil emollient base provides occlusive lipid support. The light tint from Titanium Dioxide and Mica mineral pigments adds an even-tone visual finish without functional UV protection.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003ePavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology. 2011;10(9):990-1000. PubMed PMID 22052267.\u003c\/li\u003e\n\u003cli\u003eGarre A, Martinez-Masana G, Piquero-Casals J, Granger C. Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study. Clinical, Cosmetic and Investigational Dermatology. 2017;10:473-482. PubMed PMID 29180884.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Cellular Anti-Aging Protective Day Cream. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/anti-age-day-cream\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52243085754642,"sku":"192552","price":281.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/anti-age-day-cream-square.jpg?v=1789186922"},{"product_id":"ceramide-barrier-night-cream","title":"CERAMIDE BARRIER NIGHT CREAM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eA 50 ml \/ 1.69 fl oz overnight moisturiser built on a natural Ceramide Complex (Glycosphingolipids and Glycolipids), with Sodium Hyaluronate, Tocopherol (Vitamin E), and Ascorbyl Palmitate (an oil-soluble Vitamin C ester), in a base of organic Cocoa Butter, Jojoba Seed Oil, and Sunflower Seed Oil. 99% natural origin, 27% organic origin, vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Anti-Aging, Dry Skin, and Sensitive Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eGlycosphingolipids and Glycolipids, a natural Ceramide Complex, help condition and comfort the appearance of the overnight skin barrier.\u003c\/li\u003e\n\u003cli\u003eSodium Hyaluronate, a humectant, provides surface hydration.\u003c\/li\u003e\n\u003cli\u003eCocoa Butter, Jojoba Seed Oil, and Sunflower Seed Oil, an emollient base, nourish and soften the appearance of dry skin\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: the natural Ceramide Complex (Glycosphingolipids and Glycolipids) supports the appearance of stratum corneum lipid comfort. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eGlycosphingolipids + Glycolipids (Natural Ceramide Complex), Sodium Hyaluronate, Theobroma Cacao (Cocoa) Seed Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Ascorbyl Palmitate.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Glycosphingolipids and Glycolipids (a natural Ceramide Complex); Sodium Hyaluronate (a humectant); Cocoa Butter, Jojoba, and Sunflower Seed Oil (an emollient base).\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eApply in the evening to clean skin as the final step of the routine.\u003c\/li\u003e\n\u003cli\u003ePress gently into the face and neck.\u003c\/li\u003e\n\u003cli\u003eFollow each morning with a broad-spectrum SPF 30 or higher daily.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 27% organic origin, vegan eligible. Contains naturally occurring fragrance compounds (Linalool, Limonene). Patch test on the inner forearm for 24 hours before facial use.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eGlycosphingolipids and Glycolipids form the natural Ceramide Complex documented in cosmetic literature for its role in the appearance of stratum corneum lipid comfort. The Cocoa Butter, Jojoba Seed Oil, and Sunflower Seed Oil emollient base provides occlusive lipid support and barrier-repair benefits from topical plant oils\u003csup\u003e1\u003c\/sup\u003e. Tocopherol and Ascorbyl Palmitate contribute oil-soluble antioxidants.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003eLin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences. 2018;19(1):70. DOI 10.3390\/ijms19010070. PubMed PMID 29280987.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Ceramide Barrier Night Cream. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/ceramide-barrier-night-cream\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52244756857106,"sku":"193007","price":281.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/ceramide-barrier-night-cream-square.jpg?v=1789187051"},{"product_id":"vitamin-c-serum","title":"CELLULAR ANTI-AGING ASCORBYL GLUCOSIDE SERUM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eA 30 ml \/ 1.01 fl oz stabilised Vitamin C face serum built on Ascorbyl Glucoside at 2% (a glycosylated stable Vitamin C derivative), with Ferulic Acid at 1% as an antioxidant synergist and a multi-weight Hyaluronic Acid system, on a plant-oil emollient base. 99% natural origin, 13% organic origin, vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Anti-Aging, Hyperpigmentation, and Dry Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAscorbyl Glucoside at 2%, a stable Vitamin C derivative, is converted in skin to release L-ascorbic acid, helping brighten and even the look of tone\u003csup\u003e1,2\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eFerulic Acid at 1% supports Vitamin C stability within the antioxidant network\u003csup\u003e3\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eMulti-weight Hyaluronic Acid pairs surface and penetrating molecular weights to hydrate and smooth the appearance of skin\u003csup\u003e4\u003c\/sup\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Ascorbyl Glucoside is a glycosylated stable Vitamin C derivative converted to free L-ascorbic acid in viable human epidermis. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eAscorbyl Glucoside, Ferulic Acid, Multi-Weight Hydrolyzed Hyaluronic Acid + Sodium Hyaluronate, Hippophae Rhamnoides (Sea Buckthorn) Fruit Oil, Rosa Canina (Rosehip) Fruit Oil, Tocopherol.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Ascorbyl Glucoside at 2% (a stable Vitamin C derivative, the brightening hero); Ferulic Acid at 1% (an antioxidant synergist); Multi-Weight Hyaluronic Acid (a humectant).\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eApply two to three drops to clean skin in the morning, after toner and before moisturiser.\u003c\/li\u003e\n\u003cli\u003eLayer a broad-spectrum SPF 30 or higher daily. Vitamin C pairs well with morning application under sunscreen.\u003c\/li\u003e\n\u003cli\u003eSuitable for daily morning use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 13% organic origin, vegan eligible. Contains naturally occurring fragrance allergens (Limonene, Geranyl Acetate, Linalool, Geraniol, Citronellol). Patch test on the inner forearm for 24 hours before facial use, and avoid use if you have a known sensitivity to these allergens.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eAscorbyl Glucoside is a glycosylated stable Vitamin C derivative that is converted to free L-ascorbic acid in viable human epidermis\u003csup\u003e1\u003c\/sup\u003e. In a 24-week double-blind half-face study (n=27), an ascorbyl glucoside complex significantly reduced the appearance of pigmentation on solar lentigos compared to placebo. That study used a 28% complexed concentration, while this formulation uses 2% ascorbyl glucoside\u003csup\u003e2\u003c\/sup\u003e. Ferulic Acid contributes to the canonical Vitamin C antioxidant network. Ferulic acid has been shown to stabilise a topical vitamin C and E solution and double its photoprotection, an effect cited as mechanism-class plausibility because it has not been directly tested for the ascorbyl glucoside form\u003csup\u003e3\u003c\/sup\u003e. Multi-weight Hyaluronic Acid pairs surface and penetrating molecular weights for hydration\u003csup\u003e4\u003c\/sup\u003e.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003eJacques C, Genies C, Bacqueville D, et al. Ascorbic acid 2-glucoside: an ascorbic acid pro-drug with longer-term antioxidant efficacy in skin. International Journal of Cosmetic Science. 2021;43(6):691-702. DOI 10.1111\/ics.12745. PubMed PMID 34679221.\u003c\/li\u003e\n\u003cli\u003eTakada M, Numano K, Nakano M, et al. Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos. Int J Mol Sci. 2024;25(24). DOI 10.3390\/ijms252413453. PubMed PMID 39769217.\u003c\/li\u003e\n\u003cli\u003eLin FH, Lin JY, Gupta RD, et al. Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology. 2005;125(4):826-832. DOI 10.1111\/j.0022-202X.2005.23768.x. PubMed PMID 16185284.\u003c\/li\u003e\n\u003cli\u003ePavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology. 2011;10(9):990-1000. PubMed PMID 22052267.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Cellular Anti-Aging Ascorbyl Glucoside Serum. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/vitamin-c-serum\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52244840218898,"sku":"193036","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/vitamin-c-serum-square.jpg?v=1789186842"},{"product_id":"youthful-glow-serum","title":"WATERCRESS BOTANICAL SERUM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eThe Opuliss Skin Watercress Botanical Serum is a 30 ml \/ 1.01 fl oz lightweight face serum built on a three-active stack of Multi-Weight Hyaluronic Acid, Nasturtium Officinale (Watercress) Flower\/Leaf Extract, and Sambucus Nigra (Elder) Fruit Extract, in a Sunflower Seed Oil and Glycerin base. The formula is 100% natural origin, 23% organic origin, and vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Anti-Aging and Dry Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMulti-Weight Hyaluronic Acid (Hydrolyzed Hyaluronic Acid plus Sodium Hyaluronate), a humectant, pairs surface-hydrating and stratum-corneum molecular weights for layered moisture\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eHelianthus Annuus (Sunflower) Seed Oil, an emollient plant oil, conditions and comforts the surface.\u003c\/li\u003e\n\u003cli\u003eNasturtium Officinale (Watercress) Flower\/Leaf Extract, an antioxidant botanical, and Sambucus Nigra (Elder) Fruit Extract, an anthocyanin polyphenol, support the appearance of resilient skin\u003csup\u003e2\u003c\/sup\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Multi-Weight Hyaluronic Acid, a humectant, pairs molecular weights for surface and stratum-corneum hydration. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eAqua, Glycerin, Caprylic\/Capric Triglyceride, Helianthus Annuus (Sunflower) Seed Oil, Pentylene Glycol, Cetearyl Alcohol, Glyceryl Stearate Citrate, Sodium PCA, Cellulose, Parfum, Hydrolyzed Hyaluronic Acid, Xanthan Gum, Glyceryl Caprylate, Nasturtium Officinale (Watercress) Flower\/Leaf Extract, Sambucus Nigra (Elder) Fruit Extract, Ascorbyl Palmitate, Sodium Hyaluronate, Sodium Phytate, Potassium Hydroxide, Linalool, Geraniol, Citronellol.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Multi-Weight Hyaluronic Acid (Hydrolyzed Hyaluronic Acid plus Sodium Hyaluronate), a humectant; Nasturtium Officinale (Watercress) Flower\/Leaf Extract, an antioxidant botanical; Sambucus Nigra (Elder) Fruit Extract, an anthocyanin polyphenol.\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eApply two to three drops to clean skin morning and evening, after toner and before moisturiser. The lightweight serum absorbs quickly and layers compatibly under any leave-on actives or moisturiser.\u003c\/p\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e100% natural origin, 23% organic origin, vegan eligible. Contains naturally occurring fragrance allergens (Linalool, Geraniol, Citronellol). The Watercress (Nasturtium Officinale) botanical is sourced against a supplier heavy-metal certificate of analysis. Patch test on the inner forearm for 24 hours before facial use.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003ePavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology. 2011;10(9):990-1000. PubMed PMID 22052267.\u003c\/li\u003e\n\u003cli\u003eKlimek-Szczykutowicz M, Szopa A, Ekiert H. Watercress (Nasturtium officinale) phytochemistry, pharmacology, and cosmetic applications: a comprehensive review. Phytochemistry Reviews. 2025;24(1):185-216. DOI 10.1007\/s11101-024-09965-9.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Watercress Botanical Serum. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/youthful-glow-serum\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52244854014226,"sku":"193048","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/youthful-glow-serum-square.jpg?v=1789187794"},{"product_id":"double-hydration-boost-gel-ha","title":"HYALURONIC PREBIOTIC HYDRATING GEL","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eThe Opuliss Skin Hyaluronic Prebiotic Hydrating Gel is a 30 ml \/ 1.01 fl oz lightweight aqueous gel built on Multi-Weight Hyaluronic Acid (Hydrolyzed Hyaluronic Acid plus Sodium Hyaluronate), a Microbiome Prebiotic Complex (Rhamnose, Glucose, Glucuronic Acid), Camellia Sinensis (White Tea) Leaf Extract, and Salvia Officinalis (Sage) Leaf Extract, on an Aloe Barbadensis Leaf Juice base. The formula is 99% natural origin, 11% organic origin, and vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Anti-Aging, Dry Skin, and Sensitive Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMulti-Weight Hyaluronic Acid, a humectant, pairs high-molecular-weight Sodium Hyaluronate for surface film hydration with low-molecular-weight Hydrolyzed Hyaluronic Acid for stratum corneum penetration, helping visibly plump the look of skin through sustained hydration.\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eMicrobiome Prebiotic Complex (Rhamnose, Glucose, Glucuronic Acid), sugar substrates documented as supporting cast for skin microbiome balance.\u003c\/li\u003e\n\u003cli\u003eCamellia Sinensis (White Tea) Leaf Extract, an antioxidant polyphenol, and Salvia Officinalis (Sage) Leaf Extract, a skin-conditioning botanical contributing rosmarinic and phenolic acids.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Multi-Weight Hyaluronic Acid pairs surface-film Sodium Hyaluronate with penetrating Hydrolyzed Hyaluronic Acid. Topical hyaluronic acid of different molecular weights significantly improves skin hydration. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eAloe Barbadensis (Aloe) Leaf Juice, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Rhamnose, Glucose, Glucuronic Acid, Camellia Sinensis (White Tea) Leaf Extract, Salvia Officinalis (Sage) Leaf Extract, Sodium PCA, Glycerin.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Multi-Weight Hyaluronic Acid (Hydrolyzed Hyaluronic Acid plus Sodium Hyaluronate), a dual-weight humectant hero; Microbiome Prebiotic Complex (Rhamnose, Glucose, Glucuronic Acid), a sugar-substrate humectant blend; Camellia Sinensis (White Tea) Leaf Extract, an antioxidant polyphenol.\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eApply two to three drops to clean skin morning and evening, after toner and before serum or moisturiser. The lightweight gel absorbs quickly and layers compatibly under any leave-on actives, including retinoids, Vitamin C, and AHAs.\u003c\/p\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 11% organic origin, vegan eligible. Patch test on the inner forearm for 24 hours before facial use.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eMulti-Weight Hyaluronic Acid pairs high-molecular-weight Sodium Hyaluronate for surface film hydration with low-molecular-weight Hydrolyzed Hyaluronic Acid for stratum corneum penetration. Topical hyaluronic acid of different molecular weights has been shown to improve skin hydration, with low-molecular-weight fractions associated with better penetration.\u003csup\u003e1\u003c\/sup\u003e\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003ePavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology. 2011;10(9):990-1000. PubMed PMID 22052267.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Hyaluronic Prebiotic Hydrating Gel. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/double-hydration-boost-gel-ha\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52244854341906,"sku":"193049","price":169.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/double-hydration-boost-gel-ha-square.jpg?v=1789187129"},{"product_id":"gentle-cleansing-milk","title":"ARGAN BOTANICAL CLEANSING MILK","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eThe Opuliss Skin Argan Botanical Cleansing Milk is a 190 ml \/ 6.42 fl oz lipid-rich cleansing milk built on a four-active botanical stack: Argania Spinosa (Argan) Kernel Oil, Persea Gratissima (Avocado) Oil, Paeonia Lactiflora (Peony) Root Extract, and Centaurea Cyanus (Cornflower) Flower Extract. The formula is 99% natural origin, 15% organic origin, and vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for mature, dehydrated, and dry skin seeking a barrier-respecting daily cleanse.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eArgania Spinosa (Argan) Kernel Oil, an emollient plant oil, contributes oleic and linoleic fatty acids documented for skin-conditioning and barrier-supportive comfort\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003ePersea Gratissima (Avocado) Oil, an emollient, helps condition and soften the skin during cleansing\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003ePaeonia Lactiflora (Peony) Root Extract, a skin-conditioning botanical carrying paeoniflorin, supports the look of comforted skin.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Argania Spinosa (Argan) Kernel Oil, an emollient plant oil, contributes oleic and linoleic fatty acids reviewed for skin-conditioning and barrier-supportive comfort. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eArgania Spinosa (Argan) Kernel Oil, Persea Gratissima (Avocado) Oil, Paeonia Lactiflora (Peony) Root Extract, Centaurea Cyanus (Cornflower) Flower Extract.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Argania Spinosa (Argan) Kernel Oil, an emollient plant oil; Persea Gratissima (Avocado) Oil, an emollient plant oil; Paeonia Lactiflora (Peony) Root Extract, a skin-conditioning botanical.\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cp\u003eApply two to three pumps to dry or damp skin. Massage gently across the face and neck for 30 to 60 seconds, focusing on areas with makeup or surface buildup. Rinse with lukewarm water, or remove with a damp soft cloth. Follow with toner and serum.\u003c\/p\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 15% organic origin, vegan eligible. Contains Centaurea Cyanus (Cornflower) Flower Extract, a botanical extract from the Asteraceae (daisy) plant family. Users with known sensitivity to plants in this family (ragweed, chamomile, arnica, chrysanthemum, marigold) may be at higher risk of contact sensitivity. We recommend a 24-hour patch test on the inner forearm before facial use. Contains naturally occurring fragrance allergens (Linalool, Limonene, Benzyl Salicylate, Citral).\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003eLin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences. 2018;19(1):70. DOI 10.3390\/ijms19010070. PubMed PMID 29280987.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Argan Botanical Cleansing Milk. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/gentle-cleansing-milk\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52251040710930,"sku":"194118","price":45.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/gentle-cleansing-milk-square.jpg?v=1789187242"},{"product_id":"hydrating-toner","title":"ROSA DAMASCENA HYDRATION ESSENCE","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eA 200 ml \/ 6.76 fl oz humectant-loaded toner-essence with steam-distilled Rosa Damascena (Rose) Flower Water at the second INCI position as the aqueous base and floral aromatic signature, carrying a triple humectant of Glycerin, Sodium PCA, and Sodium Hyaluronate, plus Chamomilla Recutita (Camomile) Flower Extract and Fragaria Ananassa (Strawberry) Fruit Extract. 99% natural origin, 7% organic origin, vegan.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Dry Skin and Sensitive Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSodium Hyaluronate, a glycosaminoglycan naturally present in skin, a humectant that can hold up to 1,000 times its weight in water\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eSodium PCA, a component of the skin's natural moisturising factor, a humectant and skin-conditioning agent that supports water-binding, alongside Glycerin.\u003c\/li\u003e\n\u003cli\u003eChamomilla Recutita (Camomile) Flower Extract, a skin-conditioning botanical that helps soothe and comfort.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Sodium Hyaluronate, a glycosaminoglycan humectant, binds and holds water at the skin surface to support hydration. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eRosa Damascena (Rose) Flower Water, Sodium Hyaluronate, Chamomilla Recutita (Camomile) Flower Extract, Fragaria Ananassa (Strawberry) Fruit Extract.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Sodium Hyaluronate, a humectant glycosaminoglycan; Sodium PCA, a humectant component of natural moisturising factor; Glycerin, a humectant.\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAfter cleansing morning and evening, decant a small amount onto a cotton pad or into the palm and press gently over the face and neck.\u003c\/li\u003e\n\u003cli\u003eAllow the essence to absorb before applying serum or moisturiser.\u003c\/li\u003e\n\u003cli\u003eSuitable for daily use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 7% organic origin, vegan. The aromatic profile comes from the Rosa Damascena Flower Water hydrosol. No added Parfum is listed in the supplier INCI. This product contains Chamomilla Recutita (Camomile) Flower Extract from the Asteraceae (daisy) plant family, which includes beneficial botanicals (chamomile, calendula, arnica, helichrysum) and common allergens including ragweed. If you have a known sensitivity to plants in this family (ragweed, chamomile, arnica, chrysanthemum, marigold, echinacea, or yarrow), you may be at higher risk of contact sensitivity. Rose-sensitive users should also patch test. Patch test on the inner forearm for 24 hours before use, and discontinue if a reaction occurs.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eThe hydration stack pairs three complementary humectants with a flower-water carrier. Rosa Damascena (Rose) Flower Water is a steam-distilled hydrosol of damask rose that provides the aqueous base and a light floral aromatic profile. Glycerin is the workhorse humectant, Sodium PCA is a component of the skin's natural moisturising factor listed with humectant and skin-conditioning functions in EU CosIng, and Sodium Hyaluronate completes the humectant trio. Hyaluronic acid is a glycosaminoglycan naturally present in skin that can hold up to 1,000 times its weight in water\u003csup\u003e1\u003c\/sup\u003e. Chamomilla Recutita (Camomile) Flower Extract supplies the soothing component, and Fragaria Ananassa (Strawberry) Fruit Extract contributes a trace polyphenol antioxidant. Lactic Acid and Citric Acid are present at pH-adjuster trace level only. This is not an exfoliating toner.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003ePapakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology. 2012;4(3):253-258. DOI 10.4161\/derm.21923.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Rosa Damascena Hydration Essence. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/hydrating-toner\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52251059781906,"sku":"194144","price":50.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/hydrating-toner-square.jpg?v=1789187337"},{"product_id":"retinol-alternative-eye-serum","title":"CELLULAR ANTI-AGING BIORETINOL EYE SERUM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eA 15 ml \/ 0.51 fl oz periorbital serum built on a five-active stack: Bidens Pilosa Extract, a plant-based retinol alternative that anchors the Bioretinol line, Dipalmitoyl Hydroxyproline, a collagen amino acid ester, Alteromonas Ferment Extract\u003csup\u003e3\u003c\/sup\u003e, a deep-sea marine ferment, Escin within Aesculus Hippocastanum (Horse Chestnut) Seed Extract, and Borago Officinalis (Borage) Seed Oil, with Multi-Weight Hyaluronic Acid. 100% natural origin, 22% organic origin, vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Anti-Aging, Dry Skin, and Sensitive Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBidens Pilosa Extract, a botanical retinol alternative, combined with andrographolide, improved the look of wrinkles in various areas in a human clinical trial without irritation\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eEscin from Horse Chestnut Seed Extract, a triterpene saponin, supports the appearance of vascular dark circles under the eye\u003csup\u003e2\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eMulti-Weight Hyaluronic Acid, pairing surface and penetrating molecular weights, hydrates and visibly smooths.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Bidens Pilosa Extract activates retinoid X receptor (RXR) alpha and supports extracellular matrix gene expression in laboratory models. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eBidens Pilosa Extract (Plant-Based Retinol Alternative), Dipalmitoyl Hydroxyproline (Collagen Amino Acid Ester), Alteromonas Ferment Extract, Escin + Aesculus Hippocastanum (Horse Chestnut) Seed Extract, Borago Officinalis (Borage) Seed Oil, Multi-Weight Hydrolyzed Hyaluronic Acid + Sodium Hyaluronate.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Bidens Pilosa Extract (a botanical RXR-pathway alternative); Dipalmitoyl Hydroxyproline (a collagen amino acid ester); Escin from Horse Chestnut Seed Extract (a triterpene saponin).\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eDispense a rice-grain quantity onto the ring finger and pat gently along the orbital bone from the inner corner outward.\u003c\/li\u003e\n\u003cli\u003eUse morning and evening after cleansing, before moisturiser or SPF.\u003c\/li\u003e\n\u003cli\u003eAllow 30 seconds to absorb before layering serums or sunscreen.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e100% natural origin, 22% organic origin, vegan eligible. Asteraceae botanical disclosure: this product contains Bidens Pilosa Extract from the Asteraceae (daisy) plant family, which includes beneficial botanicals (chamomile, calendula, helichrysum) and common allergens including ragweed. Users with a known sensitivity to plants in this family (ragweed, chamomile, arnica, chrysanthemum, marigold, echinacea, or yarrow) may be at higher risk of contact sensitivity. Contains naturally occurring fragrance allergens (Geraniol, Citronellol, Linalool, Citral). Patch test on the inner forearm for 24 hours before periorbital use, and avoid direct contact with the eye surface. Pregnancy and nursing topical safety data is insufficient for the active stack at cosmetic concentrations. Consult a healthcare provider before use.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eBidens Pilosa Extract supplies the botanical retinoid-pathway mechanism class. Ye 2025 reported that a fixed-combination test cream of 0.035% andrographolide plus 0.35% Bidens Pilosa Extract activated retinoid X receptor (RXR) alpha and enhanced extracellular matrix protein gene expression in dermal fibroblast and keratinocyte models. The human clinical cohort (n=14 crow's feet, n=13 under-eye, 4-week split-face versus a 0.1% retinol comparator) showed wrinkle, elasticity, and hydration improvements without irritating side effects\u003csup\u003e1\u003c\/sup\u003e. The clinical signal is fixed-combination, not Bidens monotherapy. Dieamant 2015 separately documented a standardised supercritical CO2 Bidens extract modulating RXR and RAR receptor expression in human dermal fibroblasts and ex vivo human skin fragments\u003csup\u003e4\u003c\/sup\u003e. Escin from Horse Chestnut Seed Extract is documented for reducing vascular permeability and for anti-edematous properties\u003csup\u003e2\u003c\/sup\u003e. Borago Officinalis Seed Oil delivers gamma-linolenic acid, an essential fatty acid studied in dermatology\u003csup\u003e5\u003c\/sup\u003e. Multi-Weight Hyaluronic Acid pairs surface-hydrating and stratum-corneum-penetrating molecular weights\u003csup\u003e6\u003c\/sup\u003e.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003eYe S, Lee S, Kang S, Jun SH, Kang NG. Improvement of Skin Condition Through RXR Alpha-Activating Materials. Biomolecules. 2025;15(2):296. DOI 10.3390\/biom15020296. PubMed PMID 40001599.\u003c\/li\u003e\n\u003cli\u003eGallelli L. Escin: a review of its anti-edematous, anti-inflammatory, and venotonic properties. Drug Design, Development and Therapy. 2019;13:3425-3437. DOI 10.2147\/DDDT.S207720. PubMed PMID 31631970.\u003c\/li\u003e\n\u003cli\u003eGarre A, Martinez-Masana G, Piquero-Casals J, Granger C. Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study. Clinical, Cosmetic and Investigational Dermatology. 2017;10:473-482. PubMed PMID 29180884.\u003c\/li\u003e\n\u003cli\u003eDieamant G, Pereda MdelC, Nogueira C, et al. Antiageing Mechanisms of a Standardized Supercritical CO2 Preparation of Black Jack (Bidens pilosa L.) in Human Fibroblasts and Skin Fragments. Evidence-Based Complementary and Alternative Medicine. 2015;2015:280529. DOI 10.1155\/2015\/280529. PubMed PMID 25883669.\u003c\/li\u003e\n\u003cli\u003eFenner J, Silverberg NB. Oral supplements in atopic dermatitis. Clinics in Dermatology. 2018;36(5):653-658. DOI 10.1016\/j.clindermatol.2018.05.010. PubMed PMID 30217278.\u003c\/li\u003e\n\u003cli\u003ePavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology. 2011;10(9):990-1000. PubMed PMID 22052267.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Cellular Anti-Aging Bioretinol Eye Serum. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/retinol-alternative-eye-serum\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52251138294034,"sku":"194181","price":162.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/retinol-alternative-eye-serum-square.jpg?v=1789187621"},{"product_id":"retinol-alternative-serum","title":"CELLULAR ANTI-AGING BIORETINOL SERUM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eA 30 ml \/ 1.01 fl oz plant-retinoid serum built on a five-active stack led by Bidens Pilosa Extract, a plant-based retinol alternative, with Rose Myrtle Fruit Extract, Sea Buckthorn Fruit Extract, Rosehip Fruit Oil, and Murumuru Seed Butter, plus Multi-Weight Hyaluronic Acid. 99% natural origin, 24% organic origin, vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Anti-Aging.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBidens Pilosa Extract, a retinol alternative, combined with andrographolide, improved the look of wrinkles, elasticity and hydration in a human trial without retinol's typical irritation\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eRhodomyrtus Tomentosa (Rose Myrtle) Fruit Extract, a phenolic antioxidant, supports the skin against the appearance of environmental stress.\u003c\/li\u003e\n\u003cli\u003eHippophae Rhamnoides (Sea Buckthorn) Fruit Extract helps support the appearance of the skin barrier through its flavonoids\u003csup\u003e2\u003c\/sup\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Bidens Pilosa Extract, a botanical RXR-pathway active, activates the retinoid X receptor (RXR) alpha pathway associated with the appearance of firmer, smoother skin. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eBidens Pilosa Extract (Plant-Based Retinol Alternative), Rhodomyrtus Tomentosa (Rose Myrtle) Fruit Extract, Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract, Rosa Canina (Rosehip) Fruit Oil, Astrocaryum Murumuru Seed Butter, Multi-Weight Hydrolyzed Hyaluronic Acid + Sodium Hyaluronate.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Bidens Pilosa Extract (a botanical RXR-pathway active); Rose Myrtle Fruit Extract (a phenolic antioxidant); Sea Buckthorn Fruit Extract (a flavonoid antioxidant).\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eApply two to three drops to clean skin morning and evening, pressing into the face and neck.\u003c\/li\u003e\n\u003cli\u003eLayer under moisturiser.\u003c\/li\u003e\n\u003cli\u003eApply a broad-spectrum SPF 30 or higher daily.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 24% organic origin, vegan eligible. Asteraceae botanical disclosure: this product contains Bidens Pilosa Extract from the Asteraceae (daisy) plant family, which includes beneficial botanicals (chamomile, calendula, helichrysum) and common allergens including ragweed. Users with a known sensitivity to plants in this family (ragweed, chamomile, arnica, chrysanthemum, marigold, echinacea, or yarrow) may be at higher risk of contact sensitivity. Contains naturally occurring fragrance allergens (Geraniol, Citronellol, Linalool, Citral). Patch test on the inner forearm for 24 hours before facial use.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eBidens Pilosa Extract delivers the botanical retinoid-pathway approach. Ye 2025 showed that a fixed-combination test cream of 0.035% andrographolide plus 0.35% Bidens Pilosa Extract activated retinoid X receptor (RXR) alpha and enhanced extracellular matrix protein gene expression in dermal fibroblast and keratinocyte models. The human clinical cohort (n=14 crow's feet, 4-week split-face versus 0.1% retinol comparator) showed wrinkle, elasticity, and hydration improvements without irritating side effects\u003csup\u003e1\u003c\/sup\u003e. The clinical signal is fixed-combination, not Bidens monotherapy. Dieamant 2015 separately documented a standardised supercritical CO2 Bidens extract modulating RXR and RAR receptor expression in human dermal fibroblasts and ex vivo human skin fragments\u003csup\u003e3\u003c\/sup\u003e. Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract supports the appearance of the skin barrier via a flavonoid and carotenoid antioxidant composition. Gu 2022 studied Total Flavonoids of Hippophae rhamnoides (TFH), an isolated flavonoid fraction at 0.5% and 1% TFH cream that is chemically distinct from whole Fruit Extract, so the mechanism class extends to the whole Fruit Extract in this product at supporting tier only\u003csup\u003e2\u003c\/sup\u003e. Rosa Canina (Rosehip) Fruit Oil, an emollient plant oil, conditions the skin through its linoleic and alpha-linolenic essential fatty acid composition. Multi-Weight Hyaluronic Acid pairs surface-hydrating and stratum-corneum-penetrating molecular weights\u003csup\u003e4\u003c\/sup\u003e.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003eYe S, Lee S, Kang S, Jun SH, Kang NG. Improvement of Skin Condition Through RXR Alpha-Activating Materials. Biomolecules. 2025;15(2):296. DOI 10.3390\/biom15020296. PubMed PMID 40001599.\u003c\/li\u003e\n\u003cli\u003eGu Y, Wang X, Liu F, et al. Total flavonoids of sea buckthorn (Hippophae rhamnoides L.) improve MC903-induced atopic dermatitis-like lesions. Journal of Ethnopharmacology. 2022;292:115195. DOI 10.1016\/j.jep.2022.115195. PubMed PMID 35306042.\u003c\/li\u003e\n\u003cli\u003eDieamant G, Pereda MdelC, Nogueira C, et al. Antiageing Mechanisms of a Standardized Supercritical CO2 Preparation of Black Jack (Bidens pilosa L.) in Human Fibroblasts and Skin Fragments. Evidence-Based Complementary and Alternative Medicine. 2015;2015:280529. DOI 10.1155\/2015\/280529. PubMed PMID 25883669.\u003c\/li\u003e\n\u003cli\u003ePavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology. 2011;10(9):990-1000. PubMed PMID 22052267.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Cellular Anti-Aging Bioretinol Serum. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/retinol-alternative-serum\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52251141013778,"sku":"194182","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/retinol-alternative-serum-corrected-sq.png?v=1789193489"},{"product_id":"peptide-anti-aging-serum","title":"HEXAPEPTIDE FIRMING SERUM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eA 30 ml \/ 1.01 fl oz anti-aging face serum built on a five-active composition: Hexapeptide-11 (a signal peptide), Dipalmitoyl Hydroxyproline (a collagen amino acid ester), a natural Ceramide Complex of Glycosphingolipids and Glycolipids, Phytosterols, and Blueberry Seed Oil, with a multi-weight hyaluronic acid blend. 99% natural origin, 20% organic origin, vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Anti-Aging and Dry Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHexapeptide-11, a signal peptide, is studied in cosmetic literature for the appearance of skin firmness\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eMulti-weight hyaluronic acid, a humectant pairing surface and penetrating molecular weights, helps the skin appear plumper and more hydrated\u003csup\u003e2\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eNatural Ceramide Complex (Glycosphingolipids and Glycolipids), a barrier-conditioning lipid blend that supports the appearance of a comforted, hydrated barrier.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Hexapeptide-11, a signal peptide, is documented in cosmetic literature for the signaling peptide mechanism class associated with the appearance of firmness. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eHexapeptide-11 (Signal Peptide), Dipalmitoyl Hydroxyproline (Collagen Amino Acid Ester), Glycosphingolipids + Glycolipids (Natural Ceramide Complex), Phytosterols, Vaccinium Myrtillus (Blueberry) Seed Oil, Multi-Weight Hydrolyzed Hyaluronic Acid + Sodium Hyaluronate.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Hexapeptide-11 (a signal peptide); Dipalmitoyl Hydroxyproline (a collagen amino acid ester); Glycosphingolipids and Glycolipids (a natural Ceramide Complex, barrier-conditioning lipids).\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eApply two to three drops to clean skin morning and evening, after toner and before moisturiser.\u003c\/li\u003e\n\u003cli\u003ePress gently into the face and neck.\u003c\/li\u003e\n\u003cli\u003eLayer with broad-spectrum SPF 30 or higher daily.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 20% organic origin, vegan eligible. Contains naturally occurring fragrance allergens (Linalool, Geraniol, Citronellol). Patch test on the inner forearm for 24 hours before facial use, and discontinue if irritation occurs.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eHexapeptide-11 is a signal peptide studied in cosmetic literature for the signaling peptide mechanism class associated with the appearance of skin firmness\u003csup\u003e1\u003c\/sup\u003e. Multi-weight hyaluronic acid pairs surface and penetrating molecular weights for a plumper, more hydrated look\u003csup\u003e2\u003c\/sup\u003e, and the natural Ceramide Complex of Glycosphingolipids and Glycolipids is a barrier-conditioning lipid blend.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003eSchagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. DOI 10.3390\/cosmetics4020016.\u003c\/li\u003e\n\u003cli\u003ePavicic T, Gauglitz GG, Lersch P, et al. Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. Journal of Drugs in Dermatology. 2011;10(9):990-1000. PubMed PMID 22052267.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Hexapeptide Firming Serum. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/peptide-anti-aging-serum\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52423485161746,"sku":"212310","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/peptide-anti-aging-serum-square.jpg?v=1789187569"}],"url":"https:\/\/opuliss.com\/collections\/the-precision-collection.oembed","provider":"Opuliss Beauty","version":"1.0","type":"link"}