{"product_id":"bioactive-prebiotics-jelly-serum","title":"POSTBIOTIC CALM SERUM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eA 30 ml \/ 1.01 fl oz microbiome-supportive jelly serum built on a two-active stack: Lactobacillus Ferment Lysate (a postbiotic) and Multi-Weight Hyaluronic Acid, with Sodium PCA as a natural-moisturising-factor humectant and Algin and Cellulose Gum for the weightless jelly texture. 99% natural origin, 10% organic origin, vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Dry Skin and Sensitive Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus Ferment Lysate, a postbiotic (an inanimate microbial lysate, not live bacteria), supports skin barrier function and surface comfort\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eMulti-Weight Hyaluronic Acid, pairing Hydrolyzed Hyaluronic Acid with Sodium Hyaluronate, a glycosaminoglycan humectant that helps hold water in the stratum corneum\u003csup\u003e2\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eSodium PCA, a third humectant tier and a component of skin's natural moisturising factor, for lasting hydration in a jelly that absorbs without residue.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Lactobacillus Ferment Lysate, a postbiotic, supported skin barrier markers in a reconstructed human epidermis model. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eLactobacillus Ferment Lysate (Postbiotic), Sodium PCA, Multi-Weight Hydrolyzed Hyaluronic Acid + Sodium Hyaluronate.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Lactobacillus Ferment Lysate (a postbiotic, skin-conditioning); Multi-Weight Hyaluronic Acid, Hydrolyzed Hyaluronic Acid plus Sodium Hyaluronate (a glycosaminoglycan humectant); Sodium PCA (a humectant of skin's natural moisturising factor).\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAfter cleansing and any toner step, press a small amount gently into the face and neck.\u003c\/li\u003e\n\u003cli\u003eAllow the jelly to absorb before applying moisturiser. It absorbs without residue.\u003c\/li\u003e\n\u003cli\u003eSuitable for daily morning and evening use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 10% organic origin, vegan eligible. The formulation contains Alcohol at INCI position 2 as a co-solvent, and Pogostemon Cablin (Patchouli) Oil supplies the aromatic profile, so Parfum is present at fragrance levels. Patch test on the inner forearm for 24 hours before facial use, and avoid contact with eyes.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eLactobacillus Ferment Lysate is a postbiotic (an inanimate microbial lysate). Applied to reconstructed human epidermis, a Lactobacillus rhamnosus lysate supported skin barrier proteins including filaggrin, loricrin, and the tight junction proteins claudin-1 and occludin\u003csup\u003e1\u003c\/sup\u003e. Multi-Weight Hyaluronic Acid pairs low-molecular-weight Hydrolyzed Hyaluronic Acid with higher-molecular-weight Sodium Hyaluronate. Hyaluronic acid is a glycosaminoglycan naturally present in skin that can hold up to 1,000 times its weight in water\u003csup\u003e2\u003c\/sup\u003e. In a 30-day randomised self-control study, a four-strain Lactobacillus lysate cosmetic blend improved transepidermal water loss and hydration endpoints in sensitive-skin subjects\u003csup\u003e3\u003c\/sup\u003e.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003eJung YO, Jeong H, Cho Y, et al. Lysates of a Probiotic, Lactobacillus rhamnosus, Can Improve Skin Barrier Function in a Reconstructed Human Epidermis Model. International Journal of Molecular Sciences. 2019;20(17):4289. PubMed PMID 31480681.\u003c\/li\u003e\n\u003cli\u003ePapakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology. 2012;4(3):253-258. DOI 10.4161\/derm.21923.\u003c\/li\u003e\n\u003cli\u003eCui H, Feng C, Zhang T, et al. Effects of a lotion containing probiotic ferment lysate as the main functional ingredient on enhancing skin barrier: a randomized, self-control study. Sci Rep. 2023;13(1):16879. DOI 10.1038\/s41598-023-43336-y. PubMed PMID 37803101.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Postbiotic Calm Serum. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/bioactive-prebiotics-jelly-serum\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52243102368018,"sku":"192564","price":325.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/bioactive-prebiotics-jelly-serum-square.jpg?v=1789186973","url":"https:\/\/opuliss.com\/products\/bioactive-prebiotics-jelly-serum","provider":"Opuliss Beauty","version":"1.0","type":"link"}