{"product_id":"calming-eye-cream","title":"CANNABIDIOL EYE CREAM","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\u003cp\u003eThe Opuliss Skin Cannabidiol Eye Cream is a 15 ml \/ 0.51 fl oz periorbital cream built on 1% Cannabidiol (CBD) in a Cannabis Sativa (Hemp) Seed Oil base, with horse chestnut escin, grape leaf, ginkgo biloba, multi-weight hyaluronic acid, and wild mango kernel butter. Formulated with EU-compliant cannabidiol (under 0.001% THC). 99% natural origin, 18% organic origin, vegan eligible.\u003c\/p\u003e\u003ch3\u003eHow It Works\u003c\/h3\u003e\u003cp\u003e\u003cem\u003eFormulated for Dry Skin, Redness and Rosacea, and Sensitive Skin.\u003c\/em\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eCannabidiol (CBD) at 1%, a phytocannabinoid that supports skin calming and comfort through the cutaneous endocannabinoid system.\u003c\/li\u003e\n\u003cli\u003eEscin, a vasoactive saponin from horse chestnut seed, studied for its effect on vascular permeability\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eMulti-weight hyaluronic acid, a humectant that hydrates at multiple depths of the stratum corneum\u003csup\u003e2\u003c\/sup\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003csmall\u003eHero mechanism: cannabidiol, a phytocannabinoid, interacts with the skin's endocannabinoid system to support calming and comfort. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\u003ch3\u003eIngredients\u003c\/h3\u003e\u003cp\u003eCannabis Sativa Hemp Seed Oil + Cannabidiol (CBD), Irvingia Gabonensis (Wild Mango) Kernel Butter, Aesculus Hippocastanum (Horse Chestnut) Seed Extract (Escin), Multi-Weight Hydrolyzed Hyaluronic Acid + Sodium Hyaluronate, Vitis Vinifera (Grape) Leaf Extract, Ginkgo Biloba Leaf Extract.\u003c\/p\u003e\u003cp\u003eActive ingredients: Cannabidiol (CBD) at 1%, a phytocannabinoid with a skin-calming role; Escin from horse chestnut, a triterpene saponin with a vasoactive supporting role; Ginkgo Biloba Leaf Extract, an antioxidant flavonoid. The formula is rounded out by Vitamin E (Tocopherol) and Vitamin C (Ascorbyl Palmitate) as an antioxidant supporting cast.\u003c\/p\u003e\u003ch3\u003eHow to Use\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eDispense one rice-grain amount onto the ring finger.\u003c\/li\u003e\n\u003cli\u003ePat gently along the orbital bone from the inner corner outward. Do not pull the skin.\u003c\/li\u003e\n\u003cli\u003eUse morning and evening after cleansing, before moisturiser or SPF. Allow 30 seconds to absorb.\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eSafety\u003c\/h3\u003e\u003cp\u003e99% natural origin, 18% organic origin, vegan eligible. The cannabidiol is EU-compliant at under 0.001% THC. Contains naturally derived fragrance allergens (Limonene, Linalool, Geraniol, Citral). Patch test on the inner forearm for 24 hours before use. For external use only. Avoid direct eye contact. Not recommended during pregnancy or nursing without dermatologist consultation.\u003c\/p\u003e\u003ch3\u003eReferences\u003c\/h3\u003e\u003cp\u003eEscin, the vasoactive saponin in horse chestnut seed, has been studied for its effect on vascular permeability\u003csup\u003e1\u003c\/sup\u003e, while multi-weight hyaluronic acid hydrates at multiple depths of the stratum corneum\u003csup\u003e2\u003c\/sup\u003e. Ginkgo biloba leaf extract adds an antioxidant supporting role\u003csup\u003e3\u003c\/sup\u003e, and grape leaf extract contributes a venotonic supporting role\u003csup\u003e4\u003c\/sup\u003e. The hemp seed oil and wild mango kernel butter emollient base delivers balanced omega-6 and omega-3 essential fatty acids for cosmetic comfort and barrier feel, and plant-derived fatty acid oils of this kind are classified by the US Cosmetic Ingredient Review as skin-conditioning and emollient\u003csup\u003e5\u003c\/sup\u003e, complementing the 1% cannabidiol that anchors the formula.\u003c\/p\u003e\u003col class=\"op-refs\"\u003e\n\u003cli\u003eGallelli L. Drug Design, Development and Therapy. 2019;13:3425-3437. DOI 10.2147\/DDDT.S207720. PubMed PMID 31631970.\u003c\/li\u003e\n\u003cli\u003eNi C, Zhang Z, Wang Y, Zhang Z, Guo X, Lv H. Hyaluronic acid and HA-modified cationic liposomes for promoting skin penetration and retention. Journal of Controlled Release. 2023;357:432-443. DOI 10.1016\/j.jconrel.2023.03.049. PubMed PMID 37004799.\u003c\/li\u003e\n\u003cli\u003eAbdellatif AAH, Mohammed HA, Al-Khalaf AM, et al. Drug Development and Industrial Pharmacy. 2023;49(3):1-12. DOI 10.1080\/03639045.2023.2204374. PubMed PMID 37074796.\u003c\/li\u003e\n\u003cli\u003eReuter J, Wolfle U, Korting HC, Schempp C. Which plant for which skin disease? Part 2: Dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. Journal der Deutschen Dermatologischen Gesellschaft. 2010;8(11):866-873. DOI 10.1111\/j.1610-0387.2010.07472.x. PubMed PMID 20707877.\u003c\/li\u003e\n\u003cli\u003eBurnett CL, Fiume MM, Bergfeld WF, Belsito DV, et al. Safety Assessment of Plant-Derived Fatty Acid Oils. International Journal of Toxicology. 2017;36(3 suppl):51S-129S. DOI 10.1177\/1091581817740569. PubMed PMID 29243540.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Cannabidiol Eye Cream. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/calming-eye-cream\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52244725268754,"sku":"193000","price":84.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/calming-eye-cream-square.jpg?v=1789187025","url":"https:\/\/opuliss.com\/products\/calming-eye-cream","provider":"Opuliss Beauty","version":"1.0","type":"link"}