{"product_id":"microbiome-prebiotics-face-mist","title":"POSTBIOTIC CALM MIST","description":"\u003ch3\u003eThe Formula\u003c\/h3\u003e\n\u003cp\u003eA 100 ml \/ 3.38 fl oz microbiome-supportive face mist built on a four-active stack: Lactobacillus Ferment Lysate (a postbiotic), Hydrolyzed Glycosaminoglycans, a Microbiome Prebiotic Complex of Rhamnose, Glucose, and Glucuronic Acid, and Multi-Weight Hyaluronic Acid (Hydrolyzed Hyaluronic Acid plus Sodium Hyaluronate). 99% natural origin, 7% organic origin, vegan eligible.\u003c\/p\u003e\n\u003ch3\u003eHow It Works\u003c\/h3\u003e\n\u003cp\u003e\u003cem\u003eFormulated for Dry Skin and Sensitive Skin.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLactobacillus Ferment Lysate, a postbiotic (an inanimate microbial lysate, distinct from a live probiotic), supports skin barrier function and surface comfort\u003csup\u003e1\u003c\/sup\u003e.\u003c\/li\u003e\n\u003cli\u003eMicrobiome Prebiotic Complex (Rhamnose, Glucose, Glucuronic Acid), three sugar substrates for resident commensal skin bacteria.\u003c\/li\u003e\n\u003cli\u003eMulti-Weight Hyaluronic Acid, a glycosaminoglycan humectant naturally present in skin that can hold up to 1,000 times its weight in water\u003csup\u003e2\u003c\/sup\u003e.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003csmall\u003eHero mechanism: Lactobacillus Ferment Lysate, a postbiotic, releases intracellular and extracellular metabolic contents when the fermented bacteria are lysed. No viable cells remain in the finished product. Full mechanism and citations under Details and references.\u003c\/small\u003e\u003c\/p\u003e\n\u003ch3\u003eIngredients\u003c\/h3\u003e\n\u003cp\u003eLactobacillus Ferment Lysate (Postbiotic), Hydrolyzed Glycosaminoglycans, Rhamnose + Glucose + Glucuronic Acid (Microbiome Prebiotic Complex), Multi-Weight Hydrolyzed Hyaluronic Acid + Sodium Hyaluronate.\u003c\/p\u003e\n\u003cp\u003eActive ingredients: Lactobacillus Ferment Lysate, a postbiotic (an inanimate microbial lysate) with a skin-conditioning function; Microbiome Prebiotic Complex (Rhamnose, Glucose, Glucuronic Acid), sugar substrates for resident commensal bacteria; Multi-Weight Hyaluronic Acid, a glycosaminoglycan humectant.\u003c\/p\u003e\n\u003ch3\u003eHow to Use\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHold the bottle 15 to 20 centimetres from the face and mist evenly.\u003c\/li\u003e\n\u003cli\u003eUse as a morning or midday refresh, after cleansing, or after exercise. It layers cleanly under serum, moisturiser, and makeup.\u003c\/li\u003e\n\u003cli\u003eSuitable for daily use.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eSafety\u003c\/h3\u003e\n\u003cp\u003e99% natural origin, 7% organic origin, vegan eligible. The formulation contains Alcohol at INCI position 2 as a co-solvent and preservative aid. At cosmetic-use concentration it does not produce the dehydrating profile of high-alcohol toners, and Parfum is present at fragrance levels. Patch test on the inner forearm for 24 hours before facial use. Avoid spraying directly into the eyes. Close the eyes during application.\u003c\/p\u003e\n\u003ch3\u003eReferences\u003c\/h3\u003e\n\u003cp\u003eLactobacillus Ferment Lysate is a postbiotic (an inanimate microbial lysate) produced by mechanically lysing fermented Lactobacillus bacteria and is distinct from a live probiotic. EU CosIng lists it with a skin-conditioning function. Applied to reconstructed human epidermis, a Lactobacillus rhamnosus lysate supported skin barrier proteins including filaggrin, loricrin, and tight junction proteins\u003csup\u003e1\u003c\/sup\u003e. Multi-Weight Hyaluronic Acid pairs Hydrolyzed Hyaluronic Acid with Sodium Hyaluronate. Hyaluronic acid is a glycosaminoglycan naturally present in skin that can hold up to 1,000 times its weight in water\u003csup\u003e2\u003c\/sup\u003e. The Microbiome Prebiotic Complex (Rhamnose, Glucose, Glucuronic Acid) supplies three sugar substrates for resident commensal skin bacteria. In a 30-day randomised self-control study, a four-strain Lactobacillus lysate cosmetic blend improved transepidermal water loss and hydration endpoints in sensitive-skin subjects\u003csup\u003e3\u003c\/sup\u003e.\u003c\/p\u003e\n\u003col class=\"op-refs\"\u003e\n\u003cli\u003eJung YO, Jeong H, Cho Y, et al. Lysates of a Probiotic, Lactobacillus rhamnosus, Can Improve Skin Barrier Function in a Reconstructed Human Epidermis Model. International Journal of Molecular Sciences. 2019;20(17):4289. PubMed PMID 31480681.\u003c\/li\u003e\n\u003cli\u003ePapakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology. 2012;4(3):253-258. DOI 10.4161\/derm.21923.\u003c\/li\u003e\n\u003cli\u003eCui H, Feng C, Zhang T, et al. Effects of a lotion containing probiotic ferment lysate as the main functional ingredient on enhancing skin barrier: a randomized, self-control study. Sci Rep. 2023;13(1):16879. DOI 10.1038\/s41598-023-43336-y. PubMed PMID 37803101.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp class=\"op-cite\"\u003eHow to cite this product page: Opuliss. Postbiotic Calm Mist. Opuliss Skin product page. 2026. https:\/\/opuliss.com\/products\/microbiome-prebiotics-face-mist\u003c\/p\u003e","brand":"Opuliss Beauty","offers":[{"title":"Default","offer_id":52425820209426,"sku":"212653","price":40.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0926\/9195\/5986\/files\/microbiome-prebiotics-face-mist-square.jpg?v=1789187483","url":"https:\/\/opuliss.com\/products\/microbiome-prebiotics-face-mist","provider":"Opuliss Beauty","version":"1.0","type":"link"}