UREA RENEWAL BODY CREAM
5% Hydroxyethyl Urea, a humectant and natural keratolytic, pairs with 2% Panthenol (provitamin B5) and Sodium Hyaluronate in a rich 280 ml leave-on body cream. Hydroxyethyl Urea binds water at the skin surface and softens the look of rough or thickened skin, while an organic Sunflower Seed Oil base helps hydrate and comfort dry skin during daily full-body care.
Backed by published research · references belowFormulated for Dry Skin.
- Hydroxyethyl Urea at 5%, a humectant and skin-conditioning agent, binds water at the skin surface and softens the appearance of rough or thickened skin1.
- Panthenol at 2%, a provitamin B5 humectant, binds water at the skin surface and supports the moisture barrier.
- Sodium Hyaluronate, a humectant that supports surface hydration without a tacky finish, layered over an emollient base of organic Sunflower Seed Oil and Glycerin2.
Hero mechanism: Hydroxyethyl Urea combines a hygroscopic urea backbone that binds water at the stratum corneum surface with a hydroxyethyl side chain that reduces the irritation potential of higher-concentration plain Urea. Full mechanism and citations under Details and references.
The Opuliss Skin Urea Renewal Body Cream is a 280 ml / 9.47 fl oz leave-on body emollient built on a three-active stack: 5% Hydroxyethyl Urea, a humectant and natural keratolytic, 2% Panthenol (provitamin B5), and Sodium Hyaluronate, layered over a base of organic Sunflower Seed Oil and Glycerin. Vegan eligible, with no animal-derived ingredients.
Aqua, Helianthus Annuus (Sunflower) Seed Oil*, Glycerin, Hydroxyethyl Urea, Panthenol, Caprylic/Capric Triglyceride, Sodium PCA, Sodium Hyaluronate, Tocopherol. *Ingredients from organic farming.
Active ingredients: Hydroxyethyl Urea (5%), a humectant and natural keratolytic; Panthenol (2%, provitamin B5), a humectant and skin-conditioning agent; Sodium Hyaluronate, a humectant.
Aqua, Helianthus Annuus (Sunflower) Seed Oil, Glycerin, Hydroxyethyl Urea, Polyglyceryl-6 Stearate, Cetearyl Alcohol, Panthenol, Caprylic/Capric Triglyceride, Caprylic/Capric/Myristic/Stearic Triglyceride, Dicaprylyl Carbonate, Sodium PCA, Parfum, Triethyl Citrate, Polyglyceryl-6 Behenate, Benzyl Alcohol, Xanthan Gum, Sodium Benzoate, Palmitic Acid, Stearic Acid, Lactic Acid, Potassium Sorbate, Ascorbyl Palmitate, Sodium Hyaluronate, Sodium Phytate, Tocopherol, Benzyl Salicylate, Limonene, Citrus Aurantium Bergamia Peel Oil, Citrus Aurantium Peel Oil, Citral, Linalool, Linalyl Acetate, Pinene, Cananga Odorata Oil/Extract
The ingredient list printed on your product’s packaging is always definitive; where it differs from this page, the packaging prevails.
- Apply a generous layer to clean, dry skin once or twice daily, focusing on rough or thickened areas such as elbows, knees, lower legs, and heels.
- Massage gently until fully absorbed. Suitable for daily full-body use.
- For the longest humectant wear window, apply immediately after an evening shower.
Vegan eligible, with no animal-derived ingredients. Natural-origin and organic-origin percentages are not disclosed by the manufacturer. Lactic Acid is present at pH-adjuster trace level only. It is not an active exfoliant in this body-cream format. Patch test before first regular use: apply a small amount to the inner forearm, leave undisturbed for 24 hours, and observe for redness or irritation. Hydroxyethyl Urea at 5% is documented as having a reduced irritation profile relative to higher-concentration plain Urea. A transient mild stinging sensation may occur on compromised or broken skin. EU 26-allergen disclosure (above the 0.001% leave-on labelling threshold): Parfum, Benzyl Salicylate, Limonene, Citral, Linalool, Linalyl Acetate, and citrus peel oil constituents. Avoid contact with eyes.
Hydroxyethyl Urea combines a hygroscopic urea backbone that binds water at the stratum corneum surface with a hydroxyethyl side chain that reduces the irritation potential associated with higher-concentration plain Urea, and at 5% inclusion it also helps soften the surface of rough or thickened skin1. Panthenol binds water at the skin surface and is converted in situ to Pantothenic Acid (Vitamin B5). Sodium Hyaluronate is a glycosaminoglycan naturally present in skin that can hold up to 1,000 times its weight in water, supporting surface hydration without a tacky finish2. Basic emollients with a humectant-plus-occlusive composition help maintain stratum corneum hydration on dry skin as part of a regular daily routine3.
- Akinsulie A, Bergfeld WF, Belsito DV, et al. Safety Assessment of Hydroxyethyl Urea as Used in Cosmetics. International Journal of Toxicology. 2024;43(Supplement 3):128S-134S. DOI 10.1177/10915818241237791.
- Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology. 2012;4(3):253-258. DOI 10.4161/derm.21923.
- Wollenberg A, Barbarot S, Torrelo A. Basic Emollients for Xerosis Cutis in Atopic Dermatitis: A Review of Clinical Studies. International Journal of Dermatology. 2025;64 Suppl 1:13-28. DOI 10.1111/ijd.17793. PubMed PMID 40265493.
How to cite this product page: Opuliss. Urea Renewal Body Cream. Opuliss Skin product page. 2026. https://opuliss.com/products/5-urea-2-panthenol-body-cream
The Science
Urea is a natural moisturising factor studied in cosmetics as a humectant and gentle keratolytic, helping this body cream soften and deeply hydrate the look and feel of rough, dry skin.
Source: Piquero-Casals J, et al. Dermatology and Therapy, 2021 (PMID 34596890).
INSIDE THE SCIENCE
From precision-fermented actives to biomimetic complexes, discover what makes it Opuliss.
UREA
A keratolytic humectant that hydrates and gently smooths rough, dry skin.
Source: Amin R, et al. Health Science Reports, 2024 (PMID 38505682).
PROVITAMIN B5
Hydrates, soothes, and helps support a healthy-looking barrier.
Source: CIR Expert Panel safety assessment, 2022.
MULTI-WEIGHT HYALURONIC ACID
Holds water across several depths of the skin surface for visible plumping and lasting hydration.
Source: Pavicic T, et al. Journal of Drugs in Dermatology, 2011 (PMID 22052267).
HOW TO USE
Apply a generous layer to clean, dry skin once or twice daily, focusing on rough or thickened areas such as elbows, knees, lower legs, and heels.
Massage gently until fully absorbed. Suitable for daily full-body use.
For the longest humectant wear window, apply immediately after an evening shower.
THE TEXTURE
The Opuliss difference
SCIENCE, MADE VISIBLE
Opuliss begins where the research ends. Every active is named, every claim is traceable, and nothing is left to promise alone.
Morning to night
A RITUAL, CONSIDERED
Each formula stands on its own and belongs to the whole. Layered with intention, morning and night, the routine becomes unmistakably yours.
A twenty four hour rhythm
THE SKIN KEEPS TIME
Skin is not the same at midnight as it is at nine in the morning. Across a single day its temperature, its acidity and the moisture it loses to the air each move on a rhythm of their own. Morning and night are not two routines. They are one, kept in time.
Yosipovitch G et al. Journal of Investigative Dermatology, 1998 (PMID 9424081). Sixteen volunteers sampled every two hours across a twenty four hour span.
