Melanin Rich Skin Science, concerns and routines built for deeper skin tones Featured ›
30 ml

CELLULAR ANTI-AGING BAKUCHIOL RENEWAL OIL

A dry-finish bakuchiol facial oil for anti-aging, dry skin. Bakuchiol, a photostable plant alternative to retinol, works through the same retinoid pathway with better tolerability, carried in a nourishing base of jojoba, evening primrose, rosehip, and berry seed oils.

Backed by published research · references below
$295.00

Formulated for Anti-Aging and Dry Skin.

  • Bakuchiol, a meroterpene phenol, helps improve the appearance of fine lines and uneven tone via the same retinoid pathway as retinol1.
  • Oenothera Biennis (Evening Primrose) Oil, a skin-conditioning plant oil that carries gamma-linolenic acid, an essential fatty acid2.
  • Rosa Canina (Rosehip) Fruit Oil, an emollient plant oil rich in linoleic and alpha-linolenic essential fatty acids, softens and conditions.

Hero mechanism: Bakuchiol, a meroterpene phenol, engages the same downstream retinoid pathway in skin cells as retinol, with documented comparable performance on the appearance of fine lines and hyperpigmentation over 12 weeks. Full mechanism and citations under Details and references.

A 30 ml / 1.01 fl oz dry-finish facial oil serum built on a hero composition of Bakuchiol, a photostable plant alternative to retinol, carried in a base of organic Jojoba Seed Oil with Evening Primrose, Rosehip, Strawberry, Raspberry, and Blueberry seed oils. 99% natural origin, 61% organic origin, vegan eligible.

Bakuchiol, Oenothera Biennis (Evening Primrose) Oil, Tocopherol, Rosa Canina (Rosehip) Fruit Oil.

Active ingredients: Bakuchiol (a meroterpene phenol, retinoid-pathway plant active); Evening Primrose Oil (a skin-conditioning source of gamma-linolenic acid); Rosehip Fruit Oil (an emollient plant oil rich in essential fatty acids).

Simmondsia Chinensis (Jojoba) Seed Oil, Decyl Cocoate, Dicaprylyl Carbonate, Coco-Caprylate/Caprate, Oenothera Biennis (Evening Primrose) Oil, Rosa Canina (Rosehip) Fruit Oil, Bakuchiol, Tocopherol, Fragaria Ananassa (Strawberry) Seed Oil, Rubus Idaeus (Raspberry) Seed Oil, Undecane, Parfum, Tridecane, Vaccinium Myrtillus (Blueberry) Seed Oil, Geraniol, Citronellol, Linalool, Pelargonium Graveolens Flower Oil, Geranyl Acetate

The ingredient list printed on your product’s packaging is always definitive; where it differs from this page, the packaging prevails.

  • Apply two to three drops to clean skin in the evening, pressing gently into the face and neck.
  • Layer under or over your moisturiser. Bakuchiol is photostable and comfortable for daytime use.
  • Use a broad-spectrum SPF daily as part of any anti-aging routine.

99% natural origin, 61% organic origin, vegan eligible. Contains naturally occurring fragrance allergens (Geraniol, Citronellol, Linalool, Geranyl Acetate). Bakuchiol does not share retinol's molecular structure. Topical bakuchiol pregnancy safety has not been formally established, so consult your dermatologist before use during pregnancy or nursing. Patch test on the inner forearm for 24 hours before facial use.

Bakuchiol is a meroterpene phenol with no structural resemblance to retinoids, yet it engages the same downstream retinoid pathway in skin cells. Chaudhuri and Bojanowski 2014 demonstrated, via comparative gene expression profiling in skin substitute models and human dermal fibroblasts, that bakuchiol modulates the same gene expression profile as retinol3. In a 12-week prospective, randomised, double-blind clinical trial, 0.5% bakuchiol twice daily and 0.5% retinol daily both significantly decreased wrinkle surface area and the appearance of hyperpigmentation with no statistical difference. Bakuchiol users reported less facial scaling and stinging. That evidence is specific to 0.5% bakuchiol versus 0.5% retinol1. Evening primrose oil delivers gamma-linolenic acid documented in dermatology reviews of dietary supplements. Topical evidence is mechanism-class plausibility2. Lyons 2020 showed bakuchiol significantly improved the appearance of trichloroacetic-acid-induced post-inflammatory pigmentation versus vehicle and untreated control4. Bakuchiol is photostable per the Sytheon Sytenol A Technical Data Sheet5.

  1. Dhaliwal S, Rybak I, Ellis SR, et al. Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. British Journal of Dermatology. 2018;180(2):289-296. DOI 10.1111/bjd.16918. PubMed PMID 29947134.
  2. Fenner J, Silverberg NB. Oral supplements in atopic dermatitis. Clinics in Dermatology. 2018;36(5):653-658. DOI 10.1016/j.clindermatol.2018.05.010. PubMed PMID 30217278.
  3. Chaudhuri RK, Bojanowski K. Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. International Journal of Cosmetic Science. 2014;36(3):221-30. DOI 10.1111/ics.12117. PubMed PMID 24471735.
  4. Lyons AB, Kohli I, Nahhas AF, et al. Trichloroacetic acid model to accurately capture the efficacy of treatments for postinflammatory hyperpigmentation. Archives of Dermatological Research. 2020;312(10):725-730. DOI 10.1007/s00403-020-02071-4. PubMed PMID 32253506.
  5. Sytheon Ltd. Sytenol A Technical Data Sheet. 2024. Photostability and recommended use level 0.5 to 1%.

How to cite this product page: Opuliss. Cellular Anti-Aging Bakuchiol Renewal Oil. Opuliss Skin product page. 2026. https://opuliss.com/products/natural-retinol-alternative-oil-serum

The Science

Facial renewal zone A more refined look
Facial renewal zone A more refined look

Bakuchiol is a plant-derived compound studied in cosmetics as a gentler alternative to retinol, with a randomized controlled trial reporting improvement in the appearance of photoaged skin comparable to retinol and better tolerated.

Source: Dhaliwal S, et al. British Journal of Dermatology, 2019 (PMID 29947134).

INSIDE THE SCIENCE

From precision-fermented actives to biomimetic complexes, discover what makes it Opuliss.

BAKUCHIOL

BAKUCHIOL

A gentle plant-based retinol alternative that helps smooth and firm without irritation.

Source: Dhaliwal S, et al. The British Journal of Dermatology, 2019 (PMID 29947134).

EVENING PRIMROSE

EVENING PRIMROSE

GLA-rich oil that nourishes and comforts dry, reactive skin.

Source: Gehring W, et al. Arzneimittel-Forschung, 1999 (PMID 10442214).

VITAMIN E

VITAMIN E

An antioxidant that protects lipids and keeps skin soft and conditioned.

Source: Fiume MM, et al. International Journal of Toxicology, 2018 (PMID 30235959).

The ritual

HOW TO USE

Step 1
Apply
PM

Apply two to three drops to clean skin in the evening, pressing gently into the face and neck.

Step 2
Layer what follows
AM

Layer under or over your moisturiser. Bakuchiol is photostable and comfortable for daytime use.

Step 3
Protect with SPF
AM

Use a broad-spectrum SPF daily as part of any anti-aging routine.

THE TEXTURE

CELLULAR ANTI-AGING BAKUCHIOL RENEWAL OIL, the formula photographed at macro scale
oil AS DISPENSED

The Opuliss difference

SCIENCE, MADE VISIBLE

Opuliss begins where the research ends. Every active is named, every claim is traceable, and nothing is left to promise alone.

Morning to night

A RITUAL, CONSIDERED

Each formula stands on its own and belongs to the whole. Layered with intention, morning and night, the routine becomes unmistakably yours.

A twenty four hour rhythm

THE SKIN KEEPS TIME

Skin is not the same at midnight as it is at nine in the morning. Across a single day its temperature, its acidity and the moisture it loses to the air each move on a rhythm of their own. Morning and night are not two routines. They are one, kept in time.

Yosipovitch G et al. Journal of Investigative Dermatology, 1998 (PMID 9424081). Sixteen volunteers sampled every two hours across a twenty four hour span.

CELLULAR ANTI-AGING BAKUCHIOL RENEWAL OIL

REVIEWS

Loading reviews…