Grape leaf extract, used in our formulas as an antioxidant. In its source, a grapevine leaf extract lowered an irritation signal in skin cells in the laboratory, with a weaker effect against oxidising stress, and toning was not tested.

Protection in the formula

Grape Leaf sits in our formulas for one job: defending skin against everyday environmental stress. We file it under Antioxidant Defence in this glossary for the job we use it for, and the evidence section below says how far its source goes.

Protection in the vine

The mechanism is the one stated in the summary above, and we have deliberately not extended it. Where a supplier or a competitor would reach for a bigger promise, the sentence we publish stops where the research stops.

Protection in the evidence

Our source is a peer reviewed observational or laboratory study, recorded as Sangiovanni 2019 PMID 31100904. You can read it yourself at PubMed 31100904. We grade that as solid support for the protective half of what this ingredient does.

Protection and its limits

The research behind Grape Leaf studies the ingredient, not the finished Opuliss product it sits in. It is not a trial of our formula, and we will not present it as one.

Cosmetic claims describe how skin looks and feels. Nothing here is a medical claim, and nothing here treats a condition.