
CANNABIDIOL EYE CREAM
Calm, comfort, and lasting hydration for the delicate under-eye area. This lightweight 15 ml periorbital cream pairs 1% Cannabidiol (CBD) with horse chestnut escin and multi-weight hyaluronic acid to soothe, hydrate, and help the under-eye area look refreshed and rested with daily use.
Backed by published research · references belowContains fragrance (Parfum). Full ingredients
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Formulated for Dry Skin.
- Cannabidiol (CBD) at 1%, a phytocannabinoid that supports skin calming and comfort through the cutaneous endocannabinoid system.
- Escin, a vasoactive saponin from horse chestnut seed, studied for its effect on vascular permeability1.
- Multi-weight hyaluronic acid, a humectant that hydrates at multiple depths of the stratum corneum2.
Hero mechanism: cannabidiol, a phytocannabinoid, interacts with the skin's endocannabinoid system to support calming and comfort. Full mechanism and citations under Details and references.
The Opuliss Skin Cannabidiol Eye Cream is a 15 ml / 0.51 fl oz periorbital cream built on 1% Cannabidiol (CBD) in a Cannabis Sativa (Hemp) Seed Oil base, with horse chestnut escin, grape leaf, ginkgo biloba, multi-weight hyaluronic acid, and wild mango kernel butter. Formulated with EU-compliant cannabidiol (under 0.001% THC). 99% natural origin, 18% organic origin, vegan eligible.
Cannabis Sativa Hemp Seed Oil + Cannabidiol (CBD), Irvingia Gabonensis (Wild Mango) Kernel Butter, Aesculus Hippocastanum (Horse Chestnut) Seed Extract (Escin), Multi-Weight Hydrolyzed Hyaluronic Acid + Sodium Hyaluronate, Vitis Vinifera (Grape) Leaf Extract, Ginkgo Biloba Leaf Extract.
Active ingredients:
- Cannabidiol (CBD) at 1%, a phytocannabinoid with a skin-calming role
- Escin from horse chestnut, a triterpene saponin with a vasoactive supporting role
- Ginkgo Biloba Leaf Extract, an antioxidant flavonoid
The formula is rounded out by Vitamin E (Tocopherol) and Vitamin C (Ascorbyl Palmitate) as an antioxidant supporting cast.
Aloe Barbadensis (Aloe) Leaf Juice, Glycerin, Cannabis Sativa (Hemp) Seed Oil, Glyceryl Stearate Citrate, Pentylene Glycol, Cetearyl Alcohol, Coco-Caprylate, Dicaprylyl Carbonate, Sodium PCA, Cannabidiol - Derived From Extract Or Tincture Or Resin Of Cannabis, Octyldodecanol, Irvingia Gabonensis (Wild Mango) Kernel Butter, Cellulose, Parfum/Fragrance, Caprylic/Capric Triglyceride, Palmitic Acid, Stearic Acid, Xanthan Gum, Hydrogenated Coco-Glycerides, Tocopherol, Ascorbyl Palmitate, Aqua/Water, Sodium Phytate, Vitis Vinifera (Grape) Leaf Extract, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Aesculus Hippocastanum (Horse Chestnut) Seed Extract, Potassium Hydroxide, Ginkgo Biloba (Ginkgo) Leaf Extract, Limonene, Linalool, Geraniol, Citral
The ingredient list printed on your product’s packaging is always definitive; where it differs from this page, the packaging prevails.
- Dispense one rice-grain amount onto the ring finger.
- Pat gently along the orbital bone from the inner corner outward. Do not pull the skin.
- Use morning and evening after cleansing, before moisturiser or SPF. Allow 30 seconds to absorb.
Are there any side effects?
It contains naturally derived fragrance allergens (Limonene, Linalool, Geraniol, Citral). Patch test on the inner forearm for 24 hours before use.
Does it actually work?
Hemp Seed Oil is rich in linoleic acid, the omega-6 fatty acid that a review of topical plant oils describes as having a direct role in keeping the skin's water barrier intact. It is paired here with Cannabidiol.
How do I use it?
Dispense one rice-grain amount onto the ring finger. Pat gently along the orbital bone from the inner corner outward.
What is this and who is it for?
Calm, comfort, and lasting hydration for the delicate under-eye area. This lightweight 15 ml periorbital cream pairs 1% Cannabidiol (CBD) with horse chestnut escin and multi-weight hyaluronic acid to soothe, hydrate, and help the under-eye area look refreshed and rested with daily use.
99% natural origin, 18% organic origin, vegan eligible. The cannabidiol is EU-compliant at under 0.001% THC. Contains naturally derived fragrance allergens (Limonene, Linalool, Geraniol, Citral). Patch test on the inner forearm for 24 hours before use. For external use only. Avoid direct eye contact. Not recommended during pregnancy or nursing without dermatologist consultation.
Escin, the vasoactive saponin in horse chestnut seed, has been studied for its effect on vascular permeability1, while multi-weight hyaluronic acid hydrates at multiple depths of the stratum corneum2. Ginkgo biloba leaf extract adds an antioxidant supporting role3, and grape leaf extract contributes a venotonic supporting role4. The hemp seed oil and wild mango kernel butter emollient base delivers balanced omega-6 and omega-3 essential fatty acids for cosmetic comfort and barrier feel, and plant-derived fatty acid oils of this kind are classified by the US Cosmetic Ingredient Review as skin-conditioning and emollient5, complementing the 1% cannabidiol that anchors the formula.
- Gallelli L. Drug Design, Development and Therapy. 2019;13:3425-3437. DOI 10.2147/DDDT.S207720. PubMed PMID 31631970.
- Ni C, Zhang Z, Wang Y, Zhang Z, Guo X, Lv H. Hyaluronic acid and HA-modified cationic liposomes for promoting skin penetration and retention. Journal of Controlled Release. 2023;357:432-443. DOI 10.1016/j.jconrel.2023.03.049. PubMed PMID 37004799.
- Abdellatif AAH, Mohammed HA, Al-Khalaf AM, et al. Drug Development and Industrial Pharmacy. 2023;49(3):1-12. DOI 10.1080/03639045.2023.2204374. PubMed PMID 37074796.
- Reuter J, Wolfle U, Korting HC, Schempp C. Which plant for which skin disease? Part 2: Dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. Journal der Deutschen Dermatologischen Gesellschaft. 2010;8(11):866-873. DOI 10.1111/j.1610-0387.2010.07472.x. PubMed PMID 20707877.
- Burnett CL, Fiume MM, Bergfeld WF, Belsito DV, et al. Safety Assessment of Plant-Derived Fatty Acid Oils. International Journal of Toxicology. 2017;36(3 suppl):51S-129S. DOI 10.1177/1091581817740569. PubMed PMID 29243540.
How to cite this product page: Opuliss. Cannabidiol Eye Cream. Opuliss Skin product page. 2026. https://opuliss.com/products/calming-eye-cream
The Science
Hemp Seed Oil is rich in linoleic acid, the omega-6 fatty acid that a review of topical plant oils describes as having a direct role in keeping the skin's water barrier intact. It is paired here with Cannabidiol.
Source: Arena P, et al. Molecules, 2022 (PMID 35630832). Lin TK, et al. International Journal of Molecular Sciences, 2017 (PMID 29280987).
INSIDE THE SCIENCE
From precision-fermented actives to biomimetic complexes, discover what makes it Opuliss.

MULTI-WEIGHT HYALURONIC ACID
Known for its strong water-binding potential. In a 60-day study, hyaluronic acid creams improved skin elasticity compared with a placebo cream.
Source: Pavicic T, et al. Journal of Drugs in Dermatology, 2011 (PMID 22052267).

CANNABIDIOL (CBD)
Hemp-derived cannabidiol that calms and comforts the look of stressed skin.
Source: Pareek A, et al. Pharmaceutics, 2026 (PMID 42076122).

HORSE CHESTNUT
Horse chestnut seed is the source of escin, a plant compound reviewed for supporting vein tone and for reducing how readily small blood vessels leak fluid.
Source: Gallelli L. Drug Design, Development and Therapy, 2019 (PMID 31631970).
HOW TO USE

Dispense one rice-grain amount onto the ring finger.

Pat gently along the orbital bone from the inner corner outward. Do not pull the skin.

Use morning and evening after cleansing, before moisturiser or SPF. Allow 30 seconds to absorb.
THE TEXTURE
The Opuliss difference
SCIENCE, MADE VISIBLE
Opuliss begins where the research ends. Every active is named, every claim is traceable, and nothing is left to promise alone.
Morning to night
A RITUAL, CONSIDERED
Each formula stands on its own and belongs to the whole. Layered with intention, morning and night, the routine becomes unmistakably yours.
A twenty four hour rhythm
THE SKIN KEEPS TIME
Skin is not the same at midnight as it is at nine in the morning. Across a single day its temperature, its acidity and the moisture it loses to the air each move on a rhythm of their own. Morning and night are not two routines. They are one, kept in time.
Yosipovitch G et al. Journal of Investigative Dermatology, 1998 (PMID 9424081). Sixteen volunteers sampled every two hours across a twenty four hour span.
































