CERAMIDE BARRIER NIGHT CREAM
An overnight ceramide cream that conditions and comforts the look of the skin barrier while you sleep. A natural ceramide complex works with sodium hyaluronate and a cocoa butter, jojoba, and sunflower emollient base to nourish and soften the appearance of dry skin.
Backed by published research · references belowFormulated for Anti-Aging, Dry Skin, and Sensitive Skin.
- Glycosphingolipids and Glycolipids, a natural Ceramide Complex, help condition and comfort the appearance of the overnight skin barrier.
- Sodium Hyaluronate, a humectant, provides surface hydration.
- Cocoa Butter, Jojoba Seed Oil, and Sunflower Seed Oil, an emollient base, nourish and soften the appearance of dry skin1.
Hero mechanism: the natural Ceramide Complex (Glycosphingolipids and Glycolipids) supports the appearance of stratum corneum lipid comfort. Full mechanism and citations under Details and references.
A 50 ml / 1.69 fl oz overnight moisturiser built on a natural Ceramide Complex (Glycosphingolipids and Glycolipids), with Sodium Hyaluronate, Tocopherol (Vitamin E), and Ascorbyl Palmitate (an oil-soluble Vitamin C ester), in a base of organic Cocoa Butter, Jojoba Seed Oil, and Sunflower Seed Oil. 99% natural origin, 27% organic origin, vegan eligible.
Glycosphingolipids + Glycolipids (Natural Ceramide Complex), Sodium Hyaluronate, Theobroma Cacao (Cocoa) Seed Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Ascorbyl Palmitate.
Active ingredients: Glycosphingolipids and Glycolipids (a natural Ceramide Complex); Sodium Hyaluronate (a humectant); Cocoa Butter, Jojoba, and Sunflower Seed Oil (an emollient base).
Aloe Barbadensis (Aloe) Leaf Juice, Theobroma Cacao (Cocoa) Seed Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Dicaprylyl Carbonate, Pentylene Glycol, Polyglyceryl-6 Stearate, Cetearyl Alcohol, Glycerin, Helianthus Annuus (Sunflower) Seed Cera, Butyrospermum Parkii (Shea) Butter, Olea Europaea (Olive) Oil Unsaponifiables, Sodium PCA, Palmitic Acid, Stearic Acid, Polyglyceryl-6 Behenate, Parfum, Cellulose, Rhus Verniciflua Peel Cera / Rhus Succedanea Fruit Cera, Shorea Robusta Resin, Hippophae Rhamnoides (Sea Buckthorn) Fruit Extract, Xanthan Gum, Paeonia Lactiflora (Peony) Root Extract, Sambucus Nigra (Elder) Fruit Extract, Vaccinium Macrocarpon (Cranberry) Seed Oil, Glycosphingolipids, Glycolipids, Aqua, Sodium Phytate, Ascorbyl Palmitate, Tocopherol, Lactic Acid, Sodium Hyaluronate, Linalool, Limonene
The ingredient list printed on your product’s packaging is always definitive; where it differs from this page, the packaging prevails.
- Apply in the evening to clean skin as the final step of the routine.
- Press gently into the face and neck.
- Follow each morning with a broad-spectrum SPF 30 or higher daily.
99% natural origin, 27% organic origin, vegan eligible. Contains naturally occurring fragrance compounds (Linalool, Limonene). Patch test on the inner forearm for 24 hours before facial use.
Glycosphingolipids and Glycolipids form the natural Ceramide Complex documented in cosmetic literature for its role in the appearance of stratum corneum lipid comfort. The Cocoa Butter, Jojoba Seed Oil, and Sunflower Seed Oil emollient base provides occlusive lipid support and barrier-repair benefits from topical plant oils1. Tocopherol and Ascorbyl Palmitate contribute oil-soluble antioxidants.
- Lin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. International Journal of Molecular Sciences. 2018;19(1):70. DOI 10.3390/ijms19010070. PubMed PMID 29280987.
How to cite this product page: Opuliss. Ceramide Barrier Night Cream. Opuliss Skin product page. 2026. https://opuliss.com/products/ceramide-barrier-night-cream
The Science
Ceramides are barrier lipids that make up much of the skin's outer layer, studied in cosmetics for supporting barrier function and moisture retention for a smoother, more resilient-looking surface overnight.
Source: Schild J, et al. International Journal of Cosmetic Science, 2024 (PMID 39113291).
INSIDE THE SCIENCE
From precision-fermented actives to biomimetic complexes, discover what makes it Opuliss.
MULTI-WEIGHT HYALURONIC ACID
Holds water across several depths of the skin surface for visible plumping and lasting hydration.
Source: Pavicic T, et al. Journal of Drugs in Dermatology, 2011 (PMID 22052267).
CERAMIDE COMPLEX
Natural ceramides that reinforce the barrier and help lock in moisture.
Source: Andrew PV, et al. The British Journal of Dermatology, 2025 (PMID 40408261).
VITAMIN E
An antioxidant that protects lipids and keeps skin soft and conditioned.
Source: Fiume MM, et al. International Journal of Toxicology, 2018 (PMID 30235959).
HOW TO USE
Apply in the evening to clean skin as the final step of the routine.
Press gently into the face and neck.
Follow each morning with a broad-spectrum SPF 30 or higher daily.
THE TEXTURE
The Opuliss difference
SCIENCE, MADE VISIBLE
Opuliss begins where the research ends. Every active is named, every claim is traceable, and nothing is left to promise alone.
Morning to night
A RITUAL, CONSIDERED
Each formula stands on its own and belongs to the whole. Layered with intention, morning and night, the routine becomes unmistakably yours.
A twenty four hour rhythm
THE SKIN KEEPS TIME
Skin is not the same at midnight as it is at nine in the morning. Across a single day its temperature, its acidity and the moisture it loses to the air each move on a rhythm of their own. Morning and night are not two routines. They are one, kept in time.
Yosipovitch G et al. Journal of Investigative Dermatology, 1998 (PMID 9424081). Sixteen volunteers sampled every two hours across a twenty four hour span.
